Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

22 February 2002

Dynamic MR imaging of soft tissue tumors with assessment of the rate and characterof lesion enhancement.

Małgorzata Tacikowska

Med Sci Monit 2002; 8(2): MT31-35 :: ID: 420925

Abstract

BACKGROUND: The aim of this study was to analyze the diagnostic usefulnessof dynamic MRI with determination of the coefficient of enhancement rate and the character of tumor enhancement,and to assess both parameters in the differentiation of malignant lesions. MATERIAL/METHODS: The materialconsisted of 45 patients (30 sarcomas, 15 non-malignant lesions), age 16-64 years. MRI was done usingan Elscint 2T unit, gradient echo techniques, apex angle 80 degrees. The repetition time (TR) was 80-200ms, the echo time (TE) was 2-6 ms, 1 excitation; the acquisition time (TA) was 70-80 ms. The coefficientof tissue enhancement rate was calculated in the region of interest, and expressed as percent per second(erc%/s). The limit value of erc%/s was determined. The sensitivity and specificity of MRI were calculatedin the differentiation of malignant tumors. The method of contrast filling of the tumors was assessedin successive phases after administration of gadolinium Gd-DTPA. RESULTS: Dynamic MRI with determinationof the index of tumor enhancement rate is highly sensitive (93%) and specific (73%) in the differentiationof malignant and benign lesions. The usefulness of the assessment of tumor enhancement character wasnot confirmed, since the sensitivity and specificity were 73% and 33%. Dynamic MRI with determinationof erc%/s and tumor enhancement character is highly sensitive (93%) and specific (87%). CONCLUSIONS:Dynamic MRI with determination of erc%/s and tumor enhancement character is the best method for differentialdiagnosis.

Keywords: Adolescent, Magnetic Resonance Imaging, Soft Tissue Neoplasms

Add Comment 0 Comments

Editorial

01 March 2024 : Editorial  

Editorial: First Regulatory Approvals for CRISPR-Cas9 Therapeutic Gene Editing for Sickle Cell Disease and Transfusion-Dependent β-Thalassemia

Dinah V. Parums

DOI: 10.12659/MSM.944204

Med Sci Monit 2024; 30:e944204

0:00

In Press

18 Mar 2024 : Clinical Research  

Sexual Dysfunction in Women After Tibial Fracture: A Retrospective Comparative Study

Med Sci Monit In Press; DOI: 10.12659/MSM.944136  

0:00

21 Feb 2024 : Clinical Research  

Potential Value of HSP90α in Prognosis of Triple-Negative Breast Cancer

Med Sci Monit In Press; DOI: 10.12659/MSM.943049  

22 Feb 2024 : Review article  

Differentiation of Native Vertebral Osteomyelitis: A Comprehensive Review of Imaging Techniques and Future ...

Med Sci Monit In Press; DOI: 10.12659/MSM.943168  

23 Feb 2024 : Clinical Research  

A Study of 60 Patients with Low Back Pain to Compare Outcomes Following Magnetotherapy, Ultrasound, Laser, ...

Med Sci Monit In Press; DOI: 10.12659/MSM.943732  

Most Viewed Current Articles

16 May 2023 : Clinical Research  

Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...

DOI :10.12659/MSM.940387

Med Sci Monit 2023; 29:e940387

0:00

17 Jan 2024 : Review article  

Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron Variant

DOI :10.12659/MSM.942799

Med Sci Monit 2024; 30:e942799

0:00

14 Dec 2022 : Clinical Research  

Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase Levels

DOI :10.12659/MSM.937990

Med Sci Monit 2022; 28:e937990

0:00

01 Jan 2022 : Editorial  

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...

DOI :10.12659/MSM.935952

Med Sci Monit 2022; 28:e935952

0:00

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750