Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

09 January 2002

An assessment of the effectiveness of magnetic resonance imaging in delayedsequences after administration of Gd-DTPA contrast in the detection of metastatic lesions in the brain.

Urszula Grzesiakowska, Malgorzata Tacikowska

Med Sci Monit 2002; 8(1): MT21-24 :: ID: 420960

Abstract

BACKGROUND: Advances in oncology in recent years have made it possibleto undertake radical interventions even in advanced cases. Local treatment, surgical or radiosurgical,is applied ever more frequently in cases of metastases to the brain. This requires accurate determinationof the number and location of metastases by means of imaging techniques. The goal of our research wasto establish whether the use of sequences delayed by 20-30 minutes after gadolinium injection improvesthe number of metastatic lesions detected in the brain by MRI. MATERIAL/METHODS: Twenty-eight patientswere studied, ranging in age from 24 to 72 years, diagnosed with malignant tumors and suspected metastasesto the brain. MRI examinations were performed with a 2T unit in SE T1 immediately after i.v. administrationof a 0.1 mmol/kg dose of gadolinium, and again 20-30 minutes after contrast injection; both sequenceswere done in axial projection in layers identical as in the SE T1 sequence made before gadolinium injection.The focal lesions were counted and classified by size. The number of detected lesions was calculatedin each group, comparing early and late phases after contrast injection. RESULTS: The number of all nodulesfound in the delayed sequences was significantly higher in comparison to the early phase after gadoliniuminjection. CONCLUSIONS: Delayed sequence should be used to supplement basic sequences in the diagnosisof malignant metastases to the brain in selected oncological cases.

Keywords: Brain, Contrast Media, Gadolinium DTPA, Magnetic Resonance Imaging, Sensitivity and Specificity

Add Comment 0 Comments

Editorial

01 March 2024 : Editorial  

Editorial: First Regulatory Approvals for CRISPR-Cas9 Therapeutic Gene Editing for Sickle Cell Disease and Transfusion-Dependent β-Thalassemia

Dinah V. Parums

DOI: 10.12659/MSM.944204

Med Sci Monit 2024; 30:e944204

0:00

In Press

18 Mar 2024 : Clinical Research  

Sexual Dysfunction in Women After Tibial Fracture: A Retrospective Comparative Study

Med Sci Monit In Press; DOI: 10.12659/MSM.944136  

0:00

21 Feb 2024 : Clinical Research  

Potential Value of HSP90α in Prognosis of Triple-Negative Breast Cancer

Med Sci Monit In Press; DOI: 10.12659/MSM.943049  

22 Feb 2024 : Review article  

Differentiation of Native Vertebral Osteomyelitis: A Comprehensive Review of Imaging Techniques and Future ...

Med Sci Monit In Press; DOI: 10.12659/MSM.943168  

23 Feb 2024 : Clinical Research  

A Study of 60 Patients with Low Back Pain to Compare Outcomes Following Magnetotherapy, Ultrasound, Laser, ...

Med Sci Monit In Press; DOI: 10.12659/MSM.943732  

Most Viewed Current Articles

16 May 2023 : Clinical Research  

Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...

DOI :10.12659/MSM.940387

Med Sci Monit 2023; 29:e940387

0:00

17 Jan 2024 : Review article  

Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron Variant

DOI :10.12659/MSM.942799

Med Sci Monit 2024; 30:e942799

0:00

14 Dec 2022 : Clinical Research  

Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase Levels

DOI :10.12659/MSM.937990

Med Sci Monit 2022; 28:e937990

0:00

01 Jan 2022 : Editorial  

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...

DOI :10.12659/MSM.935952

Med Sci Monit 2022; 28:e935952

0:00

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750