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eISSN: 1643-3750

Cytokine (IL-beta, IL-2, IL-4, IL-6) concentration in patients with chronic hepatitis treated with interferon-alpha

Mieczysława Czerwionka-Szaflarska, Joanna Pawłowska, Waldemar Halota

Med Sci Monit 1996; 2(5): CR584-586

ID: 500056

Published: 1996-09-02

Immunological disorders in chronic hepatitis are associated with alteration in concentrations of certain cytokines. The present study aims at assessing the effect of interferon-alpha (INF-alpha) treatment on the serum levels of IL-1 beta, IL-2, IL-4, IL-6 in patients with chronic hepatitis. Following the INF-alpha treatment, both children and adults showed increased serum IL-alpha levels as compared with those from prior to the treatment. The authors believe that assessment of serum IL-6 in patients with chronic hepatitis receiving interferon-alpha may be of prognostic significance.

Keywords: chronic hepatitis, Cytokines, interferon alpha