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eISSN: 1643-3750

Influence of serum vitamin A deficit on the effectiveness of treatment in lung cancer patients

Anna Słowik-Gabryelska

Med Sci Monit 1996; 2(5): CR599-605

ID: 500063

Published: 1996-09-02

Baseline serum vitamin A levels were studied in 162 patients with lung cancer. The possible correlation between the vitamin A levels and the histological types and staging of cancer as well as between the vitamin A levels and the treatment results was assessed. In most patients a variable serum vitamin A deficit was observed even in the early stages. The deficit increased in the advanced stages of the disease. Also, in all histological types and stages of cancer a statistically significant correlation was found between the vitamin A levels and the treatment results. A high vitamin A level was frequently, though not invariably, associated with successful treatment and long survival. A deficit correlated with ineffective treatment. The bigger the deficit was, the poorer were the treatment results and the shorter the survival.

Keywords: lung cancer, treatment, Vitamin A