01 November 1996
Primary anastomosis in experimental left colonic obstruction in rats
Romualda Wojczys, Wiktor Bednarz, Zygmunt SzydłowskiMed Sci Monit 1996; 2(6): BR707-709 :: ID: 500115
Abstract
The study was performed to evaluate the early healing of immediate primary colonic anastomoses in emergency left colonic surgery. The significance of native microflora contamination into peritoneal cavity on the anastomotic breakdown was also assessed (the effect of the peritoneal cavity contamination with native microflora on the anastomotic breakdown was also assessed). Segmental left colectomy and primary end-to-end single layer colonic anasto-moses were performed 24 hours after standardized left colonic obstruction in rats. Four days later the anastomoses were resected for morphological and histological evaluation. Additionally, before the experiment, native colonic flora was tested by rectal culture. During laparotomies peritoneal cavity cultures were taken. No animal was lost during the experiment. Eighty percent of primary colonic anastomoses healed without leakage. In 20% of animals with the contamination of the peritoneal cavity with native colonic flora, leakage of the anterior wall of the anastomosis was observed. The breakdown of primary anastomosis remains a high rate complication in emergency left colonic surgery which synergizes with the native colonic flora contamination of the peritoneal cavity.
Keywords: colonic obstruction, primary anastomosis
Editorial
01 April 2024 : Editorial
Editorial: Forty Years of Waiting for Prevention and Cure of HIV Infection – Ongoing Challenges and Hopes for Vaccine Development and Overcoming Antiretroviral Drug ResistanceDOI: 10.12659/MSM.944600
Med Sci Monit 2024; 30:e944600
In Press
06 Mar 2024 : Clinical Research
Prevalence and Variation of Medical Comorbidities in Oral Surgery Patients: A Retrospective Study at Jazan ...Med Sci Monit In Press; DOI: 10.12659/MSM.943884
08 Mar 2024 : Clinical Research
Evaluation of Foot Structure in Preschool Children Based on Body MassMed Sci Monit In Press; DOI: 10.12659/MSM.943765
15 Apr 2024 : Laboratory Research
The Role of Copper-Induced M2 Macrophage Polarization in Protecting Cartilage Matrix in OsteoarthritisMed Sci Monit In Press; DOI: 10.12659/MSM.943738
07 Mar 2024 : Clinical Research
Knowledge of and Attitudes Toward Clinical Trials: A Questionnaire-Based Study of 179 Male Third- and Fourt...Med Sci Monit In Press; DOI: 10.12659/MSM.943468
Most Viewed Current Articles
17 Jan 2024 : Review article
Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron VariantDOI :10.12659/MSM.942799
Med Sci Monit 2024; 30:e942799
14 Dec 2022 : Clinical Research
Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase LevelsDOI :10.12659/MSM.937990
Med Sci Monit 2022; 28:e937990
16 May 2023 : Clinical Research
Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...DOI :10.12659/MSM.940387
Med Sci Monit 2023; 29:e940387
01 Jan 2022 : Editorial
Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...DOI :10.12659/MSM.935952
Med Sci Monit 2022; 28:e935952