H-Index
70
Scimago Lab
powered by Scopus
Clarivate
Analytics
Formerly the IP & Science
business of Thomson Reuters

Logo




eISSN: 1643-3750

Get your full text copy in PDF

Use of a non-contact radiant heat bandage on ischemic dermal infections in an ovine model

Alexandre d’Audiffret, Scott Roethle, Alexander Tretinyak, Steven Santilli

Med Sci Monit 2002; 8(8): BR289-292

ID: 13589


Background: Chronic non-healing foot wounds are common complication in the diabetic population. Local radiant heat bandage has recently been proposed as an effective adjuvant. The purpose of this study was to evaluate the efficacy of such bandage in controlling infection in an ovine ischemic wound model.
Material/Methods: Bilateral flank ischemic wounds were created in a total of 42 sheep. 14 sheep were challenged with Pseudomonas aeruginosa (PA), 13 with Escherichia Coli (EC), and 15 with Methicillin resistant staphylococcus aureus (MRSA). The left flank was designated the treatment side and the right the control side. The radiant heat bandage was applied for a total of 10 days. The animal were
then euthanized and the wounds harvested for bacterial quantification.
Results: 39 sheep completed the study. Mean bacterial counts were has follows: for MRSA, control 7.6×105 CFU/gm vs. heated 2.0×105 CFU/gm (p=0.16); for EC, control 1.1×106 CFU/gm vs. heated 2.7×105 CFU/gm (p=0.006); PA, control 1.7×106 CFU/gm vs. heated 3.9×109 CFU/gm (p=0.001).
Conclusion: Non-contact radiant bandages controls bacterial growth in ischemic wounds infected with MRSA or EC and may potentially improve wound healing. Wounds infected with PA should no be submitted to such treatment.

This paper has been published under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) allowing to download articles and share them with others as long as they credit the authors and the publisher, but without permission to change them in any way or use them commercially.
I agree