02 March 1998
Different methods of 20% Mannitol administration on early diuresis in kidney graft recipients
Cezary Pakulski, Andrzej ŚwiniarskiMed Sci Monit 1998; 4(2): CR268-271 :: ID: 502600
Abstract
Introduction: The aim of this study was to investigate the different methods of 20% Mannitol administration on the occurrence of early diuresis in kidney graft recipients as well as on long-term kidney transplantation results. Early diuresis was defined as diuresis that exceeded the patient's own kidneys excretory function of 30 ml/kg b.m before the graft transplantation. Methods: 42 patients (21 pairs) - kidney graft recipients in 1994 - were included in the study. Each patient from a given pair received one kidney from the same donor. Both recipients from each pair were randomly included in one of the two groups. An appropriate volume of Mannitol was administered before kidney reperfusion in group I, and in group II Mannitol was administered following graft reperfusion. 20% Mannitol was administered at a dose of 0.7 g/kg b. m. with a rate infusion of 10 ml/min. Renal excretory function was evaluated in the first and second postoperative days as well as 1 month and 1 year after renal transplantation. Results: On the 1st postoperative day early diuresis occurred in 16 patients (76%) from group I and in 12 patients (57%) from group II. On the 2nd postoperative day early diuresis occurred in 62% and 48% of patients, respectively. Early diuresis had been followed by a significant decrease in the serum creatinine level. Satisfactory graft function had been found in 95% of patients from group I and in 100% of patients from group II following 30 days after renal transplantation. The one-year graft survival rate was 86% in both groups. Conclusion: Early 20% Mannitol administration significantly increases the chance for early diuresis, but has no influence on short and long-term renal transplantation results.
Keywords: renal transplantation, 20% Mannitol, early diuresis
Editorial
01 April 2024 : Editorial
Editorial: Forty Years of Waiting for Prevention and Cure of HIV Infection – Ongoing Challenges and Hopes for Vaccine Development and Overcoming Antiretroviral Drug ResistanceDOI: 10.12659/MSM.944600
Med Sci Monit 2024; 30:e944600
In Press
06 Mar 2024 : Clinical Research
Prevalence and Variation of Medical Comorbidities in Oral Surgery Patients: A Retrospective Study at Jazan ...Med Sci Monit In Press; DOI: 10.12659/MSM.943884
08 Mar 2024 : Clinical Research
Evaluation of Foot Structure in Preschool Children Based on Body MassMed Sci Monit In Press; DOI: 10.12659/MSM.943765
15 Apr 2024 : Laboratory Research
The Role of Copper-Induced M2 Macrophage Polarization in Protecting Cartilage Matrix in OsteoarthritisMed Sci Monit In Press; DOI: 10.12659/MSM.943738
07 Mar 2024 : Clinical Research
Knowledge of and Attitudes Toward Clinical Trials: A Questionnaire-Based Study of 179 Male Third- and Fourt...Med Sci Monit In Press; DOI: 10.12659/MSM.943468
Most Viewed Current Articles
17 Jan 2024 : Review article
Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron VariantDOI :10.12659/MSM.942799
Med Sci Monit 2024; 30:e942799
14 Dec 2022 : Clinical Research
Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase LevelsDOI :10.12659/MSM.937990
Med Sci Monit 2022; 28:e937990
16 May 2023 : Clinical Research
Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...DOI :10.12659/MSM.940387
Med Sci Monit 2023; 29:e940387
01 Jan 2022 : Editorial
Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...DOI :10.12659/MSM.935952
Med Sci Monit 2022; 28:e935952