Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

23 April 2009

Normative values for the 13C-mixed triglyceride breath test in two age groups

Krzysztof JonderkoACDEFG, Zuzanna DusBCD, Malgorzata SzymszalBCDF, Anna Kasicka-JonderkoADEF, Barbara Blonska-FajfrowskaFG

Med Sci Monit 2009; 15(5): CR255-259 :: ID: 869648

Abstract

Background
To investigate if age affects the results of the 13C-mixed triglyceride (13C-MTG) breath test.
Material and Method
Two groups of 12 healthy subjects (group Y, 25.0+/-0.7 years; group MA, 48.8+/-2.4 years), each comprising 6 men and 6 women, were examined. The fasted volunteers had a 349-kcal test breakfast of 50 g of white bread with 30 g of butter to which 300 mg of 13C-MTG was added. Then a series of samples of exhaled air for the measurement of 13CO2 concentration was collected over a period of 9 hours.
Results
A maximum momentary 13CO2 breath excretion of 9.6+/-0.5%dose/h at 295+/-19 min in the young subjects and of 9.4+/-0.4%dose/h at 270+/-15 min in the middle-aged volunteers was observed. The group curves of cumulative 13C recovery in breath air exhibited a virtually overlapping time course. The 6-h cumulative 13C recovery amounted to 32.01+/-1.78%dose and 31.84+/-1.73%dose in the Y and MA groups, respectively. Extension of the collection of breath air samples from the standard six to nine hours resulted in an increase in the cumulative 13C recovery by 51.5+/-3.2%. Accordingly, the 9-h cumulative 13C recovery was 47.59+/-2.26%dose and 48.28+/-2.36%dose in the Y and MA groups, respectively.
Conclusions
An age difference of over two decades does not compromise intrajejunal lipolytic activity taken as a measure of pancreatic exocrine function. Therefore reference values for the 13C-MTG breath test can be obtained from a population of healthy subjects of a relatively wide age range.

Keywords: Carbon Isotopes - analysis, Carbon Dioxide - analysis, Breath Tests, Triglycerides - analysis

Add Comment 0 Comments

Editorial

01 March 2024 : Editorial  

Editorial: First Regulatory Approvals for CRISPR-Cas9 Therapeutic Gene Editing for Sickle Cell Disease and Transfusion-Dependent β-Thalassemia

Dinah V. Parums

DOI: 10.12659/MSM.944204

Med Sci Monit 2024; 30:e944204

0:00

In Press

18 Mar 2024 : Clinical Research  

Sexual Dysfunction in Women After Tibial Fracture: A Retrospective Comparative Study

Med Sci Monit In Press; DOI: 10.12659/MSM.944136  

0:00

21 Feb 2024 : Clinical Research  

Potential Value of HSP90α in Prognosis of Triple-Negative Breast Cancer

Med Sci Monit In Press; DOI: 10.12659/MSM.943049  

22 Feb 2024 : Review article  

Differentiation of Native Vertebral Osteomyelitis: A Comprehensive Review of Imaging Techniques and Future ...

Med Sci Monit In Press; DOI: 10.12659/MSM.943168  

23 Feb 2024 : Clinical Research  

A Study of 60 Patients with Low Back Pain to Compare Outcomes Following Magnetotherapy, Ultrasound, Laser, ...

Med Sci Monit In Press; DOI: 10.12659/MSM.943732  

Most Viewed Current Articles

16 May 2023 : Clinical Research  

Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...

DOI :10.12659/MSM.940387

Med Sci Monit 2023; 29:e940387

0:00

17 Jan 2024 : Review article  

Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron Variant

DOI :10.12659/MSM.942799

Med Sci Monit 2024; 30:e942799

0:00

14 Dec 2022 : Clinical Research  

Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase Levels

DOI :10.12659/MSM.937990

Med Sci Monit 2022; 28:e937990

0:00

01 Jan 2022 : Editorial  

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...

DOI :10.12659/MSM.935952

Med Sci Monit 2022; 28:e935952

0:00

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750