Clinical Characteristics of Patients with Gastroesophageal Reflux Disease Refractory to Proton Pump Inhibitors and the Effects of Switching to 20 mg Esomeprazole on Reflux Symptoms and Quality of Life

Fuminao Takeshima; Keiichi Hashiguchi; Yasunori Onitsuka; Ken Tanigawa; Hitomi Minami; Kayoko Matsushima; Yuko Akazawa; Ken Shiozawa; Naoyuki Yamaguchi; Naota Taura; Ken Ohnita; Tatsuki Ichikawa; Hajime Isomoto; Kazuhiko Nakao

doi:10.12659/MSM.895346

31 December 2015 : Clinical Research

Clinical Characteristics of Patients with Gastroesophageal Reflux Disease Refractory to Proton Pump Inhibitors and the Effects of Switching to 20 mg Esomeprazole on Reflux Symptoms and Quality of Life

Fuminao Takeshima^ABCDEFG, Keiichi Hashiguchi^CD, Yasunori Onitsuka^B, Ken Tanigawa^B, Hitomi Minami^C, Kayoko Matsushima^CF, Yuko Akazawa^E, Ken Shiozawa^C, Naoyuki Yamaguchi^C, Naota Taura^C, Ken Ohnita^D, Tatsuki Ichikawa^D, Hajime Isomoto^DE, Kazuhiko Nakao^AG

DOI: 10.12659/MSM.895346

Med Sci Monit 2015; 21:4111-4121

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Clinical Characteristics of Patients with Gastroesophageal Reflux Disease Refractory to Proton Pump Inhibitors and the Effects of Switching to 20 mg Esomeprazole on Reflux Symptoms and Quality of Life

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