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30 July 2020 : Clinical Research  

Identification and Expression of Several Circular RNAs and Knockdown of hsa_circ_0005556 Exerts Oncogenic Functions by miR-767-5p in Gastric Cancer

Hanke Geng1BCEF, Kaixuan Li1BCDF, Qi Pan2BCEF, Shaohui Tao1BCEF, Chunjuan Li1BDF, Haiwei Zhao1BF, Xiaojun Zhao1ACEFG*

DOI: 10.12659/MSM.921163

Med Sci Monit 2020; 26:e921163

Figure 5 miR-767-5p transfection enhanced the inhibitory impacts of circ_0005556 knockdown on GC cells. (A) Expression of miR-767-5p was analyzed by qRT-PCR in GC cells transfected with si-circ_0005556 or miR-767-5p (** P<0.01 vs. scrambled group, ## P<0.01 vs. si-circRNA+NC group). (B) GC cell viability, (C) apoptosis, (D) migration, and (E) invasion were estimated by MTT, flow cytometry, wound-healing, and transwell assays, respectively, after transfection with si-circ_0005556 or miR-767-5p (** P<0.01 vs. scrambled group, ## P<0.01 vs. si-circRNA+NC group).

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750