Regulation of Keap-1/Nrf2 Signaling Pathway Is Activated by Oxidative Stress in Patients with Premature Rupture of Membranes

Wenfeng Zhang; Meng Li; Nana Li; Zonghua Liu

doi:10.12659/MSM.921757

26 June 2020 : Clinical Research

Regulation of Keap-1/Nrf2 Signaling Pathway Is Activated by Oxidative Stress in Patients with Premature Rupture of Membranes

Wenfeng Zhang^1ABCE, Meng Li^1BC, Nana Li^1BF, Zonghua Liu^1AFG*

DOI: 10.12659/MSM.921757

Med Sci Monit 2020; 26:e921757

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Figure 4 Knockdown of the expression of si-Nrf2 significantly increased the expression of Keap-1 (A) and decreased the expression of Nrf2 (B), HO-1 (C), and GSK-3β (D) at both mRNA and protein levels.

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Regulation of Keap-1/Nrf2 Signaling Pathway Is Activated by Oxidative Stress in Patients with Premature Rupture of Membranes

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