05 July 2020 : Animal Research
Therapeutic Effect of Berberine on Insomnia Rats by ErbB Signaling Pathway
Qingquan Wang1ABE, Xiaojuan Ren1C, Xingping Zhang1DG*, Guanying Wang1D, Hongxia Xu1C, Ning Deng2F, Tao Liu1D, Zhipeng Peng1BDOI: 10.12659/MSM.921831
Med Sci Monit 2020; 26:e921831
Figure 4 Enrichment analysis was used to identify the molecular regulatory mechanism of berberine therapy. (A) The key genes involved in GO function in berberine therapy. (B) The key genes involved in KEGG signaling pathway in berberine therapy. (C) Phosphorylation of ErbB2 and ErbB4 proteins. * P<0.05, ** P<0.01, *** P<0.001 versus model group. GO – Gene Ontology; KEGG – Kyoto Encyclopedia of Genes and Genomes.