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29 July 2020: Lab/In Vitro Research

Long Non-Coding RNA Nuclear Paraspeckle Assembly Transcript 1 (NEAT1)Relieves Sepsis-Induced Kidney Injury and Lipopolysaccharide (LPS)-Induced Inflammation in HK-2 Cells

Cheng Gao 1ABF* , Xiequn Zou 1BCF* , Huan Chen 2CD , Rong Shang 3BD , Bing Wang 1BD*

DOI: 10.12659/MSM.921906

Med Sci Monit 2020; 26:e921906

Figure 1 The expression level of NEAT1 in sepsis patients and healthy volunteers. (A) The relative expression level of NEAT1 in kidney tissues from sepsis patients and healthy kidney tissues was assessed with RT-qPCR assay. (B, C) BUN and serum creatinine were analyzed in kidney tissues from sepsis patients. (D–F) Western blot analysis was used to detect TNF-α, IL-6, and IL-1β levels in sepsis patients and healthy kidney tissues. * P<0.05.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750