27 June 2020 : Laboratory Research
Rab7 Is Associated with Poor Prognosis of Gastric Cancer and Promotes Proliferation, Invasion, and Migration of Gastric Cancer Cells
Huiyong Liu1ACEF, Jie Xu1DE, Qingzhi Yao1B, Zhongyi Zhang1B, Qiaonan Guo1B, Jianqing Lin1ABCE*DOI: 10.12659/MSM.922217
Med Sci Monit 2020; 26:e922217
Figure 4 Rab7 promotes the proliferation, invasion and migration of GC cells through PI3K/AKT signaling pathway. (A) Detection of PI3K and AKT protein expression in GC cell lines by Western blot analysis. β-actin was used as loading control. (B, C) The enhancement of Rab7-overexpressing on cell proliferation, invasion and migration was weakened by LY294002. Data represent the mean±SD of 3 independent experiments. * P<0.05; NS – no statistical significance, n=5 random fields, by 2-tailed t test).