21 August 2020: Animal Study
Involvement of p53, p21, and Caspase-3 in Apoptosis of Coronary Artery Smooth Muscle Cells in a Kawasaki Vasculitis Mouse Model
Minghong Deng 1ACE , Chunwang Lin 1AE* , Xianglin Zeng 1C , Jianping Zhang 1BD , Fang Wen 1C , Ziguang Liu 2B , Haiyan Wu 3B , Xiaofeng Wu 4BDOI: 10.12659/MSM.922429
Med Sci Monit 2020; 26:e922429
Figure 3 Comparison of Bcl2 (A, C) and caspase-3 (B, C) IRS values between the KD (n=12) and control groups (n=12). Comparison of Bcl2 (A) and caspase-3 (B) IRS values in the KD group and control groups. Cytoplasmic staining of Bcl2 in CASMCs was mild in mice of the KD group but was strong or moderate in mice of the control group (A). Cytoplasmic staining for caspase-3 in CASMCs was strong and moderate in mice of the KD group but mild or absent in mice of the control group (B). The IRS values for Bcl2 and caspase-3 were significantly different between the KD group and the control group (C).