Involvement of p53, p21, and Caspase-3 in Apoptosis of Coronary Artery Smooth Muscle Cells in a Kawasaki Vasculitis Mouse Model

Minghong Deng; Chunwang Lin; Xianglin Zeng; Jianping Zhang; Fang Wen; Ziguang Liu; Haiyan Wu; Xiaofeng Wu

doi:10.12659/MSM.922429

21 August 2020 : Animal Research

Involvement of p53, p21, and Caspase-3 in Apoptosis of Coronary Artery Smooth Muscle Cells in a Kawasaki Vasculitis Mouse Model

Minghong Deng^1ACE, Chunwang Lin^1AE*, Xianglin Zeng^1C, Jianping Zhang^1BD, Fang Wen^1C, Ziguang Liu^2B, Haiyan Wu^3B, Xiaofeng Wu^4B

DOI: 10.12659/MSM.922429

Med Sci Monit 2020; 26:e922429

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Figure 4 Correlation of p53 and p21 IRS values with the caspase-3 IRS in the KD group. Pearson correlation analysis revealed that the IRS for caspase-3 was positively correlated with the IRSs for p53 and p21 in the KD group (r=4.67 and 4.83; all P<0.001).

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Involvement of p53, p21, and Caspase-3 in Apoptosis of Coronary Artery Smooth Muscle Cells in a Kawasaki Vasculitis Mouse Model

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