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28 June 2020: Lab/In Vitro Research

Down-Regulation of the Mammalian Target of Rapamycin (mTOR) Pathway Mediates the Effects of the Paeonol-Platinum(II) Complex in Human Thyroid Carcinoma Cells and Mouse SW1736 Tumor Xenografts

Ling He BCDE* , Song Guo BC* , Taiyang Zhu BCD* , Chen Chen ADEF* , Kun Xu ABC*

DOI: 10.12659/MSM.922561

Med Sci Monit 2020; 26:e922561

Figure 2 The effect of the paeonol-platinum(II) (PL-Pt[II]) complex on the viability of SW1736 human anaplastic thyroid carcinoma cells and BHP7-13 human thyroid papillary carcinoma cells. The changes in SW1736 and BHP7-13 cell growth was measured at the indicated concentrations of PL-Pt(II) using the MTT assay. * P<0.05; ** P<0.02 and *** P<0.01 vs. untreated cells.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750