16 August 2020 : Animal Research
Ginkgo biloba Extract EGb761 Attenuates Bleomycin-Induced Experimental Pulmonary Fibrosis in Mice by Regulating the Balance of M1/M2 Macrophages and Nuclear Factor Kappa B (NF-κB)-Mediated Cellular Apoptosis
Ling Pan1AD*, Yuehong Lu1BCE, Zhanhua Li1BCEF, Yuping Tan1BF, Hongmei Yang1BF, Ping Ruan1CDF, Ruixiang Li1BFDOI: 10.12659/MSM.922634
Med Sci Monit 2020; 26:e922634
Figure 1 EGb761 suppresses pulmonary inflammation induced by bleomycin (BLM) in mice. (A) Pulmonary inflammation of mice was evaluated by lung alveolitis score after treatment with BLM for 28 days. Lung tissues from normal mice (B), BLM-treated group (C), low-dose EGb761 group (D), mild-dose EGb761 group (E), and high-dose EGb761 group (F) were stained with hematoxylin and eosin; magnifications were 200×. All data are shown as mean±standard deviation (n=5). * P<0.05 vs. normal group; # P<0.05 vs. BLM group.