16 August 2020 : Animal Research
Ginkgo biloba Extract EGb761 Attenuates Bleomycin-Induced Experimental Pulmonary Fibrosis in Mice by Regulating the Balance of M1/M2 Macrophages and Nuclear Factor Kappa B (NF-κB)-Mediated Cellular Apoptosis
Ling Pan1AD*, Yuehong Lu1BCE, Zhanhua Li1BCEF, Yuping Tan1BF, Hongmei Yang1BF, Ping Ruan1CDF, Ruixiang Li1BFDOI: 10.12659/MSM.922634
Med Sci Monit 2020; 26:e922634
Figure 3 EGb761 suppresses bleomycin (BLM)-induced proinflammatory cytokines in the early stage. Mouse peripheral blood was collected on day 7 after BLM treatment. Levels of proinflammatory cytokines in serum, including tumor necrosis (TNF)-a (A), interleukin (IL)-1β (B), and IL-6 (C), were detected by enzyme-linked immunosorbent assay kit. All data are shown as mean±standard deviation (n=5). ** P<0.0001 vs. normal group; ## P<0.0001 vs. BLM group.