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25 September 2020: Lab/In Vitro Research

Long Non-Coding RNA Paternally Expressed Imprinted Gene 10 (PEG10) Elevates Diffuse Large B-Cell Lymphoma Progression by Regulating Kinesin Family Member 2A (KIF2A) via Targeting MiR-101-3p

Jin Zhao 1BCF* , Liping Su 1BCD* , Jianjun Jiang 2ACE*

DOI: 10.12659/MSM.922810

Med Sci Monit 2020; 26:e922810

Figure 1 PEG10 and KIF2A are upregulated in DLBCL tissues and cells. (A, B) Detection of PEG10 and KIF2A level by RT-qPCR. (C) The protein level of KIF2A was measured by western blot. (D) RT-qPCR was performed to examine the level of PEG10 and KIF2A in C1R-neo, SU-DHL-8, and OCI-LY-8 cells. (E) The protein level of KIF2A in C1R-neo, SU-DHL-8, and OCI-LY-8 cells was measured by western blot. (F) Pearson correlation analysis revealed a positive relationship between PEG10 and KIF2A (R2=0.3173, P=0.0034). * P<0.05. PEG10 – paternally expressed imprinted gene 10; KIF2A – kinesin family member 2A; DLBCL – diffuse large B-cell lymphoma; RT-qPCR – real-time quantitative polymerase chain reaction.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750