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25 September 2020: Lab/In Vitro Research

Long Non-Coding RNA Paternally Expressed Imprinted Gene 10 (PEG10) Elevates Diffuse Large B-Cell Lymphoma Progression by Regulating Kinesin Family Member 2A (KIF2A) via Targeting MiR-101-3p

Jin Zhao 1BCF* , Liping Su 1BCD* , Jianjun Jiang 2ACE*

DOI: 10.12659/MSM.922810

Med Sci Monit 2020; 26:e922810

Figure 4 KIF2A overexpression reverses the effects of PEG10 knockdown on the progression of DLBCL. (A, B) The mRNA and protein level of KIF2A in SU-DHL-8 and OCI-LY-8 cells. (C, D) Measurement of cell proliferation and apoptosis by MTT and flow cytometry, respectively. (E, F) Transwell assays used for the measurement of the migratory and invasive abilities of SU-DHL-8 and OCI-LY-8 cells. * P<0.05. KIF2A – kinesin family member 2A; DLBCL,– diffuse large B-cell lymphoma; RT-qPCR – real-time quantitative polymerase chain reaction.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750