Celastrol Inhibits Migration and Invasion of Triple-Negative Breast Cancer Cells by Suppressing Interleukin-6 via Downregulating Nuclear Factor-κB (NF-κB)

Fei Yan; Zihong Wu; Zihui Li; Li Liu

doi:10.12659/MSM.922814

13 September 2020: Clinical Research

Celastrol Inhibits Migration and Invasion of Triple-Negative Breast Cancer Cells by Suppressing Interleukin-6 via Downregulating Nuclear Factor-κB (NF-κB)

Fei Yan ^BCDE , Zihong Wu ^BCD , Zihui Li ^ABCD , Li Liu ^BCDE*

DOI: 10.12659/MSM.922814

Med Sci Monit 2020; 26:e922814

Authors information Article notes Copyright and License information

View HTML version

Figure 2 The influence of celastrol on migration and invasion of TNBC cells. (A, B) Cell migration was assessed in MDA-MB-231 and MDA-MB-468 cells after exposure to various doses of celastrol for 24 h by transwell assay. (C, D) Cell invasion was detected after treatment with various doses of celastrol for 24 h via transwell analysis. * P<0.05 vs. the non-treated group (0 μM).

Back to the Article

Celastrol Inhibits Migration and Invasion of Triple-Negative Breast Cancer Cells by Suppressing Interleukin-6 via Downregulating Nuclear Factor-κB (NF-κB)

Your Privacy