22 July 2020: Lab/In Vitro Research
Myoglobin Mediates Autophagy of NRK-52E in Rat Renal Tubular Epithelial Cells Via the Pink1/Parkin Signaling Pathway
Zhiguo Chen 123ABCD* , Jinxiang Wang 1ABCD* , Jiao He 1BCD , Haojun Fan 24ADG , Shike Hou 24ABCDEFG* , Qi Lv 24BCD*DOI: 10.12659/MSM.923045
Med Sci Monit 2020; 26:e923045
Figure 5 Effect of autophagy promoter Rapamycin and Pink1-siRNA on apoptosis of NRK-52E by TUNEL. (Aa, Ab) Control; (Ac, Ad): Rapamycin; (Ae, Af) Rapacymin+Pink1-siRNA; (Ag, Ah) Myoglobin; (Ai, Aj) Myoglobin+Pink1-siRNA. (B) The apoptosis rates of NRK-52E cells after treated with autophagy promoter rapamycin and Pink1-siRNA were detected by TUNEL assay in different groups. Compared with group CON, * P<0.05; compared with group RAP, & P<0.05; compared with group RAP+Pin, @ P<0.05; compared with group MYO, # P<0.05.