Protective Effects of Ischemic Postconditioning on Livers in Rats with Limb Ischemia-Reperfusion via Glycogen Synthase Kinase 3 beta (GSK-3β)/Fyn/Nuclear Receptor-Erythroid-2-Related Factor (Nrf2) Pathway

Qibing Niu; Wanli Sun; Quan Chen; Yang Long; Wanjun Cao; Shiqi Wen; Anqiang Li; Fang Dong; Hao Shi

doi:10.12659/MSM.923049

20 July 2020 : Animal Research

Protective Effects of Ischemic Postconditioning on Livers in Rats with Limb Ischemia-Reperfusion via Glycogen Synthase Kinase 3 beta (GSK-3β)/Fyn/Nuclear Receptor-Erythroid-2-Related Factor (Nrf2) Pathway

Qibing Niu^1CDEF, Wanli Sun^1BCDEF, Quan Chen^1AEG*, Yang Long^1EF, Wanjun Cao^1BC, Shiqi Wen^1BC, Anqiang Li^1DE, Fang Dong^1BE, Hao Shi^1EF

DOI: 10.12659/MSM.923049

Med Sci Monit 2020; 26:e923049

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Figure 8 Analysis of GSK-3β/Fyn/Nrf2 mRNA expression in liver tissue. Rats were divided into the SO group, I/R group, IPC group, and IPO group. RT-qPCR was used to detect the mRNA levels of (A) Nrf2, (B) Fyn, and (C) GSK-3β in liver tissues. Compared with SO, * P<0.05; compared with I/R, # P<0.05.

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Protective Effects of Ischemic Postconditioning on Livers in Rats with Limb Ischemia-Reperfusion via Glycogen Synthase Kinase 3 beta (GSK-3β)/Fyn/Nuclear Receptor-Erythroid-2-Related Factor (Nrf2) Pathway

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