08 July 2020: Animal Study
Letrozole Rat Model Mimics Human Polycystic Ovarian Syndrome and Changes in Insulin Signal Pathways
Jinbang Xu 1AEG** , Jingjing Dun 1CDE* , Juan Yang 1DF , Junxin Zhang 1BF , Qiuping Lin 1B , Mingqing Huang 2B , Feng Ji 3B , Lishan Huang 3B , Xiumi You 1B , Ying Lin 3ABEG*DOI: 10.12659/MSM.923073
Med Sci Monit 2020; 26:e923073
Figure 1 Sex steroid concentrations in Letrozole+HFD, Letrozole, HFD, and control groups of rats. Serum testosterone, progesterone, and estradiol levels were determined by RIA. Data are presented as mean±SEM of 6 rats and analyzed by one-way ANOVA with Dunnett’s post hoc test. * P 0.05, ** P 0.01, *** P 0.001 compared with control group. NS – Not significant.