08 July 2020 : Animal Research
Letrozole Rat Model Mimics Human Polycystic Ovarian Syndrome and Changes in Insulin Signal Pathways
Jinbang Xu1AEG*, Jingjing Dun1CDE, Juan Yang1DF, Junxin Zhang1BF, Qiuping Lin1B, Mingqing Huang2B, Feng Ji3B, Lishan Huang3B, Xiumi You1B, Ying Lin3ABEGDOI: 10.12659/MSM.923073
Med Sci Monit 2020; 26:e923073
Figure 1 Sex steroid concentrations in Letrozole+HFD, Letrozole, HFD, and control groups of rats. Serum testosterone, progesterone, and estradiol levels were determined by RIA. Data are presented as mean±SEM of 6 rats and analyzed by one-way ANOVA with Dunnett’s post hoc test. * P 0.05, ** P 0.01, *** P 0.001 compared with control group. NS – Not significant.