08 July 2020 : Animal Research
Letrozole Rat Model Mimics Human Polycystic Ovarian Syndrome and Changes in Insulin Signal Pathways
Jinbang Xu1AEG*, Jingjing Dun1CDE, Juan Yang1DF, Junxin Zhang1BF, Qiuping Lin1B, Mingqing Huang2B, Feng Ji3B, Lishan Huang3B, Xiumi You1B, Ying Lin3ABEGDOI: 10.12659/MSM.923073
Med Sci Monit 2020; 26:e923073
Figure 2 Vaginal smears in Letrozole+HFD, Letrozole, HFD, and control groups of rats. (A) Vaginal smear from a Letrozole+HFD rat. (B) Vaginal smear from a Letrozole rat. 2a & 2b – leukocytes. (C) Vaginal smears from an HFD rat, showing a regular estrus cycle. (D) Vaginal smears from a control rat, showing a regular estrus cycle. C1, D1 – proestrus; C2, D2 – estrus; C3, D3 – metestrus; C4, D4 – diestrus.