08 July 2020 : Animal Research
Letrozole Rat Model Mimics Human Polycystic Ovarian Syndrome and Changes in Insulin Signal Pathways
Jinbang Xu1AEG*, Jingjing Dun1CDE, Juan Yang1DF, Junxin Zhang1BF, Qiuping Lin1B, Mingqing Huang2B, Feng Ji3B, Lishan Huang3B, Xiumi You1B, Ying Lin3ABEGDOI: 10.12659/MSM.923073
Med Sci Monit 2020; 26:e923073
Figure 5 Blood glucose levels and AUC of glucose and insulin tolerance tests in Letrozole+HFD, Letrozole, HFD, and control groups of rats were measured with a Bayer Contour Glucometer. (A) Blood glucose during glucose tolerance tests. (B) AUC of glucose tolerance tests. (C) Blood glucose during insulin tolerance tests. (D) AUC of insulin tolerance tests. Data are presented as mean±SEM of 6 rats and analyzed by one-way ANOVA with Dunnett’s post hoc test. * P 0.05, ** P 0.01 compared with control group. # P 0.05, ## P 0.01 compared with Letrozole group.