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13 July 2020: Clinical Research

Long-Chain Non-Coding RNA Metastasis-Related Lung Adenocarcinoma Transcript 1 (MALAT1) Promotes the Proliferation and Migration of Human Pulmonary Artery Smooth Muscle Cells (hPASMCs) by Regulating the MicroRNA-503 (miR-503)/Toll-Like Receptor 4 (TLR4) Signal Axis

Meng He 1ABCDEF , Juxin Shen 1ABCDF , Chunyi Zhang 1ABCD , Yefeng Chen 1BCDF , Weisi Wang 2BCD , Kelong Tao 3EG*

DOI: 10.12659/MSM.923123

Med Sci Monit 2020; 26:e923123

Figure 3 Low expression of microRNA-503 (miR-503) in plasma and hypoxic hPASMCs in patients with pulmonary hypertension (PAH). (A) Plasma miR-503 levels in plasma samples from patients with PAH and healthy controls. (B) Receiver operating curve (ROC) analysis for the diagnosis of PAH based on plasma miR-503 level. (C) miR-503 levels in hypoxic and non-hypoxic hPASMC cells.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750