29 August 2020>: Animal Study
Mesenchymal Stem Cells Decrease M1/M2 Ratio and Alleviate Inflammation to Improve Limb Ischemia in Mice
Ye Song 1ABCEF , Tian-Jie Zhang 2BCF , Yuan Li 3BCF , Yuan Gao 4ACD*DOI: 10.12659/MSM.923287
Med Sci Monit 2020; 26:e923287
Figure 2 Transplanted PMSCs ameliorated limb ischemic injury and rescued blood perfusion in the ischemic hind limb. (A) Representative images from the HE staining at day 7 and 14 after the procedure. (B) Quantification of muscle fiber number from the HE staining images at day 7 and 14 after the procedure. (C) Representative images from the Masson’s trichrome staining at day 7 and 14 after the procedure. (D) Quantification of fibrotic area from the Masson’s trichrome staining images at days 7 and 14 after the procedure. # P<0.05 for PMSCs group versus PBS group. Data are represented as mean±SEM.