Figure 8 The docking model of compounds with MMP9, MMP3, and MMP1. Binding model of berberine (A), isorhamnetin (B), quercetin (C), and wogonin (D) on the molecular surface of MMP9. The interaction model of berberine (a), isorhamnetin (b), quercetin (c), and wogonin (d) with MMP9. Binding model of berberine (E), isorhamnetin (F), quercetin (G), and wogo0nin (H) on the molecular surface of MMP3. The interaction model of berberine (e), isorhamnetin (f), quercetin (g), and wogonin (h) with MMP3. Binding model of berberine (I), isorhamnetin (J), quercetin (K), and wogonin (L) on the molecular surface of MMP1. The interaction model of berberine (i), isorhamnetin (j), quercetin (k), and wogonin (l) with MMP1. The ligands in binding model and interaction model are colored in green and within the dashed line, respectively. The length of the bond was added on the bond.