16 December 2020: Animal Study
Network Pharmacology Study of the Hepatoprotective Effects of Quercetin-Containing Traditional Chinese Medicine, , and Validation of Quercetin as an Anti-Liver Injury Agent in a Mouse Model of Liver Injury
Wei Lin 12ABCDEF* , Yuhan Wu 3ABCDF* , Jingjing Wang 3BCDF* , Han Lin 2BCDF* , Xiuming Xu 1ADF , Guanrong He 4A* , Bizhu He 23AG* , Xiaokai Ma 12AF*DOI: 10.12659/MSM.923533
Med Sci Monit 2020; 26:e923533
Figure 8 Effects of carbon tetrachloride (CCl4) and quercetin (Que) on protein expression of nuclear factor-kappa B (NF-κB) p65 and phosphorylated IκBα (p-IκBα) in hepatic tissue of mice. (A) Western blotting analysis of NF-κB p65 and p-IκBα. (B) Quantification of the relative protein expression levels of NF-κB p65 and p-IκBα. All data were expressed as mean ±standard deviation (SD) (n=5). * p<0.05, ** p<0.01 and ***p<0.001 compared with the mice treated with carbon tetrachloride (CCl4).