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06 August 2020: Lab/In Vitro Research

Cyclin-Dependent Kinase 1 (CDK1) is Co-Expressed with CDCA5: Their Functions in Gastric Cancer Cell Line MGC-803

Zhigang Huang 1AEG* , Shizhuo Zhang 1BEF* , Jinlin Du 1BF , Xing Zhang 1B , Weijian Zhang 1C , Zhaowei Huang 1C , Ping Ouyang 2ADE*

DOI: 10.12659/MSM.923664

Med Sci Monit 2020; 26:e923664

Figure 3 Upregulation of CDCA5 and CDK1 in gastric cancer. (A) The gene expression profile of CDCA5 across all tumor samples and matched normal tissues, based on the expression of CDCA5 from the The Cancer Genome Atlas (TCGA) various types of cancer research cohort data sets, generated by the GEPIA website, the height of bar represents the median expression of certain tumor type or normal tissue. (B) The gene expression profile of CDK1 across all tumor samples and paired normal tissues. (C) Analysis of TCGA gastric cancer tissue data(n=408) and match TCGA normal and GTEx data (n=211) through the GEPIA website, to obtain CDCA5 expression levels. (D) Analysis of TCGA gastric cancer tissue data (n=408) and match TCGA normal and GTEx data (n=211) through the GEPIA website, to obtain CDK1 expression levels (Log2FC=1, P-value=0.01).

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750