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29 June 2020: Lab/In Vitro Research

WNT974 Inhibits Proliferation, Induces Apoptosis, and Enhances Chemosensitivity to Doxorubicin in Lymphoma Cells by Inhibiting Wnt/β-Catenin Signaling

Senmin Chen A , Xiuli Yuan B , Huanli Xu C , Meng Yi E , Sixi Liu G* , Feiqiu Wen F*

DOI: 10.12659/MSM.923799

Med Sci Monit 2020; 26:e923799

Figure 6 WNT974 enhanced the sensitivity of HUT-78 and BJAB lymphoma cells to doxorubicin. Cell growth inhibition (proportion of dead cells) of (A) HUT-78 cells and (B) BJAB cells treated with indicated reagents (n=3). Dox, doxorubicin. *** P<0.001 vs. control; ### P<0.001 vs. Dox; @@@ P<0.001 vs. WNT974.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750