Long Non-Coding RNA (lncRNA) Small Nucleolar RNA Host Gene 15 (SNHG15) Alleviates Osteoarthritis Progression by Regulation of Extracellular Matrix Homeostasis

Yunping Chen; Hongna Guo; Lang Li; Dingsu Bao; Feng Gao; Qiang Li; Qi Huang; Xin Duan; Zhou Xiang

doi:10.12659/MSM.923868

09 July 2020: Lab/In Vitro Research

Long Non-Coding RNA (lncRNA) Small Nucleolar RNA Host Gene 15 (SNHG15) Alleviates Osteoarthritis Progression by Regulation of Extracellular Matrix Homeostasis

Yunping Chen ^1AB* , Hongna Guo ^1AB* , Lang Li ^23A , Dingsu Bao ^24B , Feng Gao ^3C , Qiang Li ^3D , Qi Huang ^3D , Xin Duan ^2F , Zhou Xiang ^2AG*

DOI: 10.12659/MSM.923868

Med Sci Monit 2020; 26:e923868

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Figure 1 Construction of the ceRNA network of KLF4 for OA. (A) Volcano plot showing differentially expressed mRNAs between human OA and normal cartilage tissues in the GSE114007 dataset. (B) The expression patterns of the top 30 downregulated lncRNAs and KLF4. (C) The ceRNA network of KLF4 for OA.

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Long Non-Coding RNA (lncRNA) Small Nucleolar RNA Host Gene 15 (SNHG15) Alleviates Osteoarthritis Progression by Regulation of Extracellular Matrix Homeostasis

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