09 July 2020 : Laboratory Research
Long Non-Coding RNA (lncRNA) Small Nucleolar RNA Host Gene 15 (SNHG15) Alleviates Osteoarthritis Progression by Regulation of Extracellular Matrix Homeostasis
Yunping Chen1AB, Hongna Guo1AB, Lang Li23A, Dingsu Bao24B, Feng Gao3C, Qiang Li3D, Qi Huang3D, Xin Duan2F, Zhou Xiang2AG*DOI: 10.12659/MSM.923868
Med Sci Monit 2020; 26:e923868
Figure 8 Hypermethylation of SNHG15 promoter region in OA cartilage tissues. (A) Methylation sites of SHNG15 promoter region. (B) Methylation levels of SHNG15 promoter region in OA and normal cartilage tissues as shown by MSP assay; (C) qRT-PCR results showing SHNG15 expression in OA chondrocytes treated with 5-Aza. *** p<0.001.