28 August 2020 : Clinical Research
Circ_cse1l Inhibits Colorectal Cancer Proliferation by Binding to eIF4A3
Bin Xu1ABCDEF, Ning Yang1BCDF, Yabin Liu1BCDF, Peng Kong2ACE, Mei Han2AG, Binghui Li1ABCDEFG*DOI: 10.12659/MSM.923876
Med Sci Monit 2020; 26:e923876
Figure 3 Overexpression of circ_cse1l inhibits CRC cell proliferation while reducing PCNA expression. HT29 and HCT116 cells were transfected with a circ_cse1l overexpression vector and an empty vector (NC). (A) CCK-8 and (B) colony formation assays, showing that overexpression of circ_cse1l inhibited the proliferation of HT29 and HCT116 cells. (C) Western blotting experiments, showing that circ_cse1l overexpression reduced the expression of PCNA protein in HT29 and HCT116 cells. * P<0.05, ** P<0.01.