16 July 2020>: Animal Study
Calcitonin Gene-Related Peptide Attenuates LPS-Induced Acute Kidney Injury by Regulating Sirt1
Pingli Liu ACDF , Dongmei Shi ABEG*DOI: 10.12659/MSM.923900
Med Sci Monit 2020; 26:e923900
Figure 4 Silence of Sirt1 attenuates the protective effect of CGRP on HK-2 cells. (A, B) Western blot and RT-PCR results of Sirt1; (C, D) IF staining of KIM-1 and NGAL (magnification ×400); (E, F) ELISA results of IL-1β and TNF-α; (G) RT-PCR results of IL-1β and TNF-α. (* P<0.05 vs. the control group, # P<0.05 vs. the LPS group and ## P<0.05 vs. the LPS+CGRP group).