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20 July 2020: Animal Study

Pyrazolo[4,3-c]pyridine-4-one (PP-4-one) Exhibits Anti-Epileptogenic Effect in Rat Model of Traumatic Epilepsy by Mammalian Target of Rapamycin (mTOR) Signaling Pathway Downregulation

Jungong Jin 1BCD , Xi Shen 2BCF , Lu Tian 3BCD , Guoyishi He 1BCD , Ying Zhang 3ADEF*

DOI: 10.12659/MSM.923919

Med Sci Monit 2020; 26:e923919

Figure 2 Effect of PP-4-one on behavioral seizures. The PTE rats treated with or without PP-4-one treatment were subjected to measurement of behavioral seizures. * P<0.02 and ** P<0.02 vs. the vehicle-treated rats.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750