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19 July 2020: Database Analysis

Systematic Profiling of Alternative Splicing for Sarcoma Patients Reveals Novel Prognostic Biomarkers Associated with Tumor Microenvironment and Immune Cells

Chuan Hu 1ABCEF , Yuanhe Wang 1ABC , Chuan Liu 2DEF , Rui Shen 1DE , Bo Chen 3F , Kang Sun 1B , Huili Rao 4C , Lin Ye 3E , Jianjun Ye 3C , Shaoqi Tian 1ABCDEF*

DOI: 10.12659/MSM.924126

Med Sci Monit 2020; 26:e924126

Figure 7 Correlation network between OS-AS events (A, B) and DFS-AS events (C, D) and SFs in SARC. The majority of prognostic AS events with poor prognosis (green dots) were positively (red lines) correlated with the expression of SFs (blue dots), while the majority of AS events with good prognosis (red dots) were negatively (green lines) correlated with the expression of SFs. AS – alternative splicing; OS – overall survival; DFS – disease-free survival; SF – splicing factor; SARC – sarcoma.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750