19 July 2020: Database Analysis
Systematic Profiling of Alternative Splicing for Sarcoma Patients Reveals Novel Prognostic Biomarkers Associated with Tumor Microenvironment and Immune Cells
Chuan Hu 1ABCEF , Yuanhe Wang 1ABC , Chuan Liu 2DEF , Rui Shen 1DE , Bo Chen 3F , Kang Sun 1B , Huili Rao 4C , Lin Ye 3E , Jianjun Ye 3C , Shaoqi Tian 1ABCDEF*DOI: 10.12659/MSM.924126
Med Sci Monit 2020; 26:e924126
Figure 9 AS-based clusters significantly associated with prognosis, immune microenvironment scores, and immune cells. (A–C) Unsupervised clustering analysis based on the overlapping prognostic AS events identified 3 clusters. (D) Kaplan-Meier survival curve showing the OS probability over time for 3 clusters. (E) Kaplan-Meier survival curve showing the DFS probability over time for 3 clusters. (F) Heat map showing the distribution of 22 immune cells between 3 clusters. (G–I) The immune score, stromal score, and estimate score between AS-based clusters. AS – alternative splicing; OS – overall survival; DFS – disease-free survival.