28 July 2020 : Laboratory Research
CircKIAA0907 Retards Cell Growth, Cell Cycle, and Autophagy of Gastric Cancer In Vitro and Inhibits Tumorigenesis In Vivo via the miR-452-5p/KAT6B Axis
Lingyu Zhu1BCDE, Chunfei Wang1CDEF, Shengquan Lin2BCDE, Lei Zong1ABCD*DOI: 10.12659/MSM.924160
Med Sci Monit 2020; 26:e924160
Figure 1 CircKIAA0907 expression was lessened in gastric cancer (GC) tissues and cells. (A) Genomic location of KIAA0907 gene and circKIAA0907. (B, C) Level of circKIAA0907 was assayed using quantitative real-time polymerase chain reaction (qRT-PCR) in GC tissues (B) and cells (C). (D–G) qRT-PCR analysis of circKIAA0907 and KIAA0907 was implemented in HGC27 and AGS cells after treatment with actinomycin D (D, E) and RNase R (F, G). (H, I) CircKIAA0907 localization was analyzed through comparison with glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and U6 via qRT-PCR detection. * P<0.05.