Figure 3 Effect of miR-188-3p on VSMCs. (A) The effects of ox-LDL with different treatment durations and concentrations on the viability of VSMCs were detected using the MTT assay. (B) The establishment of miR-188-3p overexpression and low-expression cell models was validated using qRT-PCR. (C) The effect of miR-188-3p on VSMCs proliferation was examined using the MTT assay. (D) The effect of miR-188-3p on the proliferation of VSMCs was examined using the BrdU assay. (E) The effect of miR-188-3p on the migration of VSMCs was examined using the Transwell assay. (F) The effect of miR-188-3p on apoptosis of VSMCs was examined using flow cytometry. ** P<0.01, and *** P<0.001. In A, ** P<0.01, and *** P<0.001, compared with the 0 mg/L group after 24 h of ox-LDL treatment; & P<0.05, and &&& P<0.001, respectively, compared with the 0 mg/L group after 48 h of ox-LDL treatment.