28 June 2020: Lab/In Vitro Research
Meteorin-Like (METRNL) Attenuates Myocardial Ischemia/Reperfusion Injury-Induced Cardiomyocytes Apoptosis by Alleviating Endoplasmic Reticulum Stress via Activation of AMPK-PAK2 Signaling in H9C2 Cells
Ling Xu A , Yinlian Cai CD , Yaoguo Wang B , Chaoxiang Xu C**DOI: 10.12659/MSM.924564
Med Sci Monit 2020; 26:e924564
Figure 7 (A, B) METRNL overexpression induced activation of AMPK-PAK2 signaling cascade. The expressions of p-AMPK, AMPK and PAK2 were determined by western blot. Error bars represent the mean±SEM from three independent experiments. **** P<0.001 versus Control; ## P<0.01, ### P<0.001 versus OGD/R 12 hours. METRNL – Meteorin-like; AMPK – 5′ AMP-activated protein kinase; PAK2 – p21-activated kinase 2; SEM – standard error of the mean.