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07 September 2020: Animal Study

A Composite Tissue Engineered Bone Material Consisting of Bone Mesenchymal Stem Cells, Bone Morphogenetic Protein 9 (BMP9) Gene Lentiviral Vector, and P3HB4HB Thermogel (BMSCs-LV-BMP9-P3HB4HB) Repairs Calvarial Skull Defects in Rats by Expression of Osteogenic Factors

Cheng Zhou 1BCDEF , Chuan Ye 2BCDF , Chen Zhao 1BCD , Junyi Liao 1BCF , Yuwan Li 1BC , Hong Chen 1BF , Wei Huang 1ADEG*

DOI: 10.12659/MSM.924666

Med Sci Monit 2020; 26:e924666

Figure 8 BMSC+LV-BMP9+P3HB4HB composite bone repair material demonstrated good repair ability for defect tissues of calvarial defect rats. The skull tissues in rat of sham group, calvarial defect model group, BMSC+LV+P3HB4HB group, and BMSC+LV-BMP9+P3HB4HB group are illustrated. BMSCs – bone mesenchymal stem cells.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750