The Role of the NOD1/Rip2 Signaling Pathway in Myocardial Remodeling in Spontaneously Hypertensive Rats

Feng-Yi Liu; Bing-Qian Fang; Ling-Min Sun; Xiu-Zhen Zhang; Jin-Li Liu; Yun Yang; Wen-Hua Zhang; Xiu-Li Wang; Yan-Chun Ding

doi:10.12659/MSM.924748

28 August 2020 : Animal Research

The Role of the NOD1/Rip2 Signaling Pathway in Myocardial Remodeling in Spontaneously Hypertensive Rats

Feng-Yi Liu^1ABCEF, Bing-Qian Fang^12ABCDEF, Ling-Min Sun^3BDF, Xiu-Zhen Zhang^3BCF, Jin-Li Liu^1ABCDF, Yun Yang^4BCDF, Wen-Hua Zhang^4BCDF, Xiu-Li Wang^3BCDF, Yan-Chun Ding^1ABCDEFG*

DOI: 10.12659/MSM.924748

Med Sci Monit 2020; 26:e924748

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Figure 7 (A, C) Immunohistochemical staining showing the expression of the NOD1 and Rip2 proteins in the myocardial tissue from rats of different ages. (B, D) Semi-quantitative analysis of the expression of the NOD1 and Rip2 proteins in the myocardium from rats of different ages measured using immunohistochemical staining. * P<0.05 compared with WKY rats of the same age, and # P<0.05 compared with 8-week-old SHRs. NOD1 – nucleotide-binding oligomerization domain 1; Rip2 – receptor-interacting protein 2; SHRs – spontaneously hypertensive rats; WKY – Wistar-Kyoto.

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The Role of the NOD1/Rip2 Signaling Pathway in Myocardial Remodeling in Spontaneously Hypertensive Rats

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