28 August 2020>: Animal Study
The Role of the NOD1/Rip2 Signaling Pathway in Myocardial Remodeling in Spontaneously Hypertensive Rats
Feng-Yi Liu 1ABCEF* , Bing-Qian Fang 12ABCDEF , Ling-Min Sun 3BDF , Xiu-Zhen Zhang 3BCF , Jin-Li Liu 1ABCDF , Yun Yang 4BCDF , Wen-Hua Zhang 4BCDF , Xiu-Li Wang 3BCDF , Yan-Chun Ding 1ABCDEFG*DOI: 10.12659/MSM.924748
Med Sci Monit 2020; 26:e924748
Figure 7 (A, C) Immunohistochemical staining showing the expression of the NOD1 and Rip2 proteins in the myocardial tissue from rats of different ages. (B, D) Semi-quantitative analysis of the expression of the NOD1 and Rip2 proteins in the myocardium from rats of different ages measured using immunohistochemical staining. * P<0.05 compared with WKY rats of the same age, and # P<0.05 compared with 8-week-old SHRs. NOD1 – nucleotide-binding oligomerization domain 1; Rip2 – receptor-interacting protein 2; SHRs – spontaneously hypertensive rats; WKY – Wistar-Kyoto.