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20 August 2020: Lab/In Vitro Research

Long Non-Coding RNA (lncRNA) NEAT1 Aggravates Cerebral Ischemia-Reperfusion Injury by Suppressing the Inhibitory Effect of miR-214 on PTEN

Shouyin Shen 1CDE , Liang Ma 1CDE , Feng Shao 2BC , Li Jin 2DEF , Zhaolian Bian 3ABFG*

DOI: 10.12659/MSM.924781

Med Sci Monit 2020; 26:e924781

Figure 1 miR-214 relieved the cerebral ischemia-reperfusion-induced cerebral infarction. (A) The efficacy of miR-214 agomir and miR-214 antagomir was detected with RT-PCR. (B) 2,3,5-triphenyltetrazolium chloride staining sections of brain tissues. (C) Proportions of cerebral infarction were determined with the formula: Cerebral infarction rate (%)=infarct area/total area×100%. ** p<0.01; ***p<0.001.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750