20 August 2020: Lab/In Vitro Research
Long Non-Coding RNA (lncRNA) NEAT1 Aggravates Cerebral Ischemia-Reperfusion Injury by Suppressing the Inhibitory Effect of miR-214 on PTEN
Shouyin Shen 1CDE , Liang Ma 1CDE , Feng Shao 2BC , Li Jin 2DEF , Zhaolian Bian 3ABFG*DOI: 10.12659/MSM.924781
Med Sci Monit 2020; 26:e924781
Figure 5 lncRNA NEAT1 targeted and inhibited the expression of miR-214 while miR-214 targeted and suppressed the expression of PTEN. (A) The sequences of mature miR-214 and putative target sites of wild-type PTEN. (B) Luciferase activity was determined in the miR-214 mimic and negative control groups. (C) The sequences of mature miR-214 and putative target sites of wild-type lncRNA NEAT1. (D) Luciferase activity was assessed in the miR-214 mimic and negative control groups. *** p<0.001.