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20 August 2020: Lab/In Vitro Research

Long Non-Coding RNA (lncRNA) NEAT1 Aggravates Cerebral Ischemia-Reperfusion Injury by Suppressing the Inhibitory Effect of miR-214 on PTEN

Shouyin Shen 1CDE , Liang Ma 1CDE , Feng Shao 2BC , Li Jin 2DEF , Zhaolian Bian 3ABFG*

DOI: 10.12659/MSM.924781

Med Sci Monit 2020; 26:e924781

Figure 6 lncRNA NEAT1 attenuated the remission effect of miR-214 on cerebral ischemia-reperfusion injury. (A) The levels of miR-214 in brain tissues were determined by RT-PCR after overexpression of lncRNA NEAT1. (B) TUNEL staining was performed to detect apoptosis in brain tissues after the overexpression of lncRNA NEAT1. (C) The levels of MDA, SOD, and CAT in brain tissues were determined after the overexpression of lncRNA NEAT1. * p<0.05; *** p<0.001.

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Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750