HMGA1 Promotes Hepatic Metastasis of Colorectal Cancer by Inducing Expression of Glucose Transporter 3 (GLUT3)

Meijing Yang; Yang Guo; Xiaoyun Liu; Naiqing Liu

doi:10.12659/MSM.924975

29 September 2020 : Clinical Research

HMGA1 Promotes Hepatic Metastasis of Colorectal Cancer by Inducing Expression of Glucose Transporter 3 (GLUT3)

Meijing Yang^1ABC, Yang Guo^1DE, Xiaoyun Liu^2E, Naiqing Liu^3ABCDEF*

DOI: 10.12659/MSM.924975

Med Sci Monit 2020; 26:e924975

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Figure 1 Expression of HMGA1 in CRCLM. (A) The metastasis of CRC was pathologically confirmed by HE staining. (B) HMGA1 expression in 73 CRCLMs was detected using IHC. Patients were categorized into HMGA1 low and high expression groups. (C) HMGA1 expression was detected with qRT-PCR in the 17 synchronous CRCLM tissues. (D) HMGA1 mRNA in normal colon tissues, CRC, and CRCLM was compared with mRNA sequencing.

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HMGA1 Promotes Hepatic Metastasis of Colorectal Cancer by Inducing Expression of Glucose Transporter 3 (GLUT3)

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