29 October 2020: Lab/In Vitro Research
Centrosome Protein 78 Is Overexpressed in Muscle-Invasive Bladder Cancer and Is Associated with Tumor Molecular Subtypes and Mutation Signatures
Xiaoli Huang 12ABCDEF* , Yang Yan 3ABCDEF* , Rong Wei 2BD , Hu Liu 2CD , Xingchen Zhu 2BD , Dexi Bi 2ACFG , Qing Wei 12AEG* , Xudong Yao 3AE*DOI: 10.12659/MSM.925197
Med Sci Monit 2020; 26:e925197
Figure 2 CEP78 overexpression confirmed in clinical samples collected by this study. (A) Comparison of the relative CEP78 expression in fresh-frozen tumor and adjacent normal tissues from 28 MIBC patients with Mann-Whitney test. (B) IHC straining scores of CEP78 in FFPE tumor and adjacent normal tissues from 33 MIBC patients compared with Mann-Whitney test or Wilcoxon signed rank test. The Mann-Whitney test p value is shown in the figure; while the Wilcoxon signed rank test p value also was <0.001. (C) Representative IHC staining images of the tumor and matched adjacent normal tissues. Images for one pair are placed in one row. All images were separately taken. Scale bar, 100 μm. Medians and interquartile ranges are shown for (A) and (B).